Biopsy (Large, >2.5 cm) – Brief Discussion

Definition:
A large biopsy involves the removal of a tissue sample larger than 2.5 cm from the affected organ or lesion for diagnostic evaluation.

Purpose / Clinical Significance:

• Provides sufficient tissue for accurate histopathological examination
• Useful when small biopsies are inconclusive or when multiple tests (e.g., histology, immunohistochemistry, molecular studies, culture) are needed
• Helps diagnose tumors, infections, or inflammatory diseases